Clinical Trials Continued…
Phase II: Enrolls a larger group of volunteers (several dozen to a several hundred) who have the targeted disease or condition in order to evaluate a drug’s effectiveness and further assess safety. Phase II trials typically last one to two years and can last longer if it’s difficult to recruit or follow up on patients.
If you are interested in what the results of a recent successful Phase II trial look like, you can check out this [OPTIONAL] press release and [OPTIONAL] slide deck from a company named 89bio reporting on the Phase II results of their drug, pegozafermin, which treats liver disease and hypertriglyceridemia.
Phase III: Encompasses a larger-scale study involving hundreds to thousands of patients to confirm a drug’s efficacy, monitor side effects, compare the drug to existing treatments and/or a placebo, and gather more comprehensive safety data. Phase III trials generally run for two to five or more years.
A recent (and record-breaking) example of a successful Phase III trial was on Pfizer’s Covid Vaccine, which involved over 46,000 participants! You can check out an [OPTIONAL] informative infographic on the study here, or get into more depth on the [OPTIONAL] data here.
Curious about Moderna’s Phase III Covid Vaccine data? You can check it out here [OPTIONAL].
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